This report is written for the dozens of professionals and students who have e-mailed me over the past few years asking questions about the toxicology, uses, and environmental control of the chemical aniline.
The current American Conference of Governmental Industrial Hygienist TLVs(tm) (threshold limit value) for aniline [CAS # 62-53-3] are:
2 ppm Skin toxin. Note: A3 a known carcinogen in animals which may be relevant to humans.
The BEI (Biological Exposure Indices) is 50 mg/g creatinine, 1.5% of hemoglobin, measured as total p-aminophenol in urine and methhemoglobin in blood. These determinants are nonspecific. Blood measurements are subject to background readings and are semi-quantitative, that is only useful as a screening test.
The OSHA PEL (Permissible Exposure Limit) is:
5 ppm [19 mg/m(3)] Skin toxin, according to Title 29 of the Code of Federal Regulations Subpart Z 1910.1000 TABLE Z-1.
Steven R. Pressman
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